South America

South America Cruises

Combine Cruise Line Offers With Our Southwest Cruises Exclusives
  • You May Qualify for One or More South America Offers
Recommended Sailings

SOUTH AMERICA CRUISES

  • MSC Poesia
    3.1 rating out of 5  (249 reviews)

    9 Night South America

    MSC Poesia

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Camboriu, Brazil
    • Ilhabela, Brazil
    • Buzios, Brazil
    • Rio De Janeiro, Brazil
    Sailing Dates:
    • January 2025
    • February 2025
    interior from
    $1,356
    $151pernight
    oceanview from
    $1,516
    $168pernight
    balcony from
    $1,686
    $187pernight
    suite from
    $2,696
    $300pernight
    All the Cruise Line Offers & More:
    • Limited-Time Exclusive: Earn 2 Points per eligible $1 spent
    • Member Exclusive: Earn up to 10,000 bonus points on eligible sailings!
    • Rapid Rewards® Member Base Offer: Earn 1 point per eligible $1 spent
    • Escape to Sea: Reduced Rates!
     
    Interior from $1,356
    ($151pernight)
    3.1 rating out of 5  (249 reviews)
  • MSC Poesia
    3.1 rating out of 5  (249 reviews)

    9 Night South America

    MSC Poesia

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Porto Belo, Brazil
    • Ilhabela, Brazil
    • Buzios, Brazil
    • Rio De Janeiro, Brazil
    Sailing Dates:
    • March 2025
    interior from
    Call for availability
    oceanview from
    Call for availability
    balcony from
    $1,901
    $211pernight
    suite from
    $2,721
    $302pernight
    All the Cruise Line Offers & More:
    • Limited-Time Exclusive: Earn 2 Points per eligible $1 spent
    • Member Exclusive: Earn up to 10,000 bonus points on eligible sailings!
    • Rapid Rewards® Member Base Offer: Earn 1 point per eligible $1 spent
    • Escape to Sea: Reduced Rates!
     
    Balcony from $1,901
    ($211pernight)
    3.1 rating out of 5  (249 reviews)
  • Sapphire Princess
    4 rating out of 5  (568 reviews)

    18 Night Brazilian Adventure

    Sapphire Princess

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • Basseterre, St. Kitts
    • Fortaleza, Brazil
    • Rio De Janeiro, Brazil
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    Sailing Dates:
    • November 2024
    interior from
    $1,311
    $73pernight
    oceanview from
    $1,329
    $74pernight
    balcony from
    $1,609
    $89pernight
    suite from
    $2,329
    $129pernight
    All the Cruise Line Offers & More:
    • Limited-Time Exclusive: Earn 2 Points per eligible $1 spent
    • Member Exclusive: Earn up to 10,000 bonus points on eligible sailings!
    • Rapid Rewards® Member Base Offer: Earn 1 point per eligible $1 spent
    • Drop & Go Sale: Limited Time Reduced Rates!
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Here Comes the Sun Sale: Save up to 40%
     
    Interior from $1,311
    ($73pernight)
    4 rating out of 5  (568 reviews)
  • Sapphire Princess
    4 rating out of 5  (568 reviews)

    18 Night Andes & South America

    Sapphire Princess

    Departing from: San Antonio (Santiago), Chile
    Ports of Call:
    • Coquimbo (La Serena), Chile
    • General San Martin (Pisco), Peru
    • Callao (Lima), Peru
    • Manta, Ecuador
    • Puntarenas, Costa Rica
    • Puerto Vallarta, Mexico
    • Cabo San Lucas, Mexico
    • San Pedro (Los Angeles), California
    Sailing Dates:
    • March 2025
    interior from
    $1,529
    $85pernight
    oceanview from
    $1,632
    $91pernight
    balcony from
    $2,489
    $138pernight
    suite from
    $3,089
    $172pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Limited-Time Exclusive: Earn 2 Points per eligible $1 spent
    • Member Exclusive: Earn up to 10,000 bonus points on eligible sailings!
    • Rapid Rewards® Member Base Offer: Earn 1 point per eligible $1 spent
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Here Comes the Sun Sale: Save up to 40%
     
    Interior from $1,529
    ($85pernight)
    4 rating out of 5  (568 reviews)
  • Majestic Princess
    4.4 rating out of 5  (418 reviews)

    18 Night Brazilian Adventure

    Majestic Princess

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Rio De Janeiro, Brazil
    • Fortaleza, Brazil
    • Dominica
    • Basseterre, St. Kitts
    • Ft. Lauderdale (Port Everglades), Florida
    Sailing Dates:
    • January 2025
    interior from
    $1,749
    $97pernight
    oceanview from
    Not Available
    balcony from
    $2,246
    $125pernight
    suite from
    $2,559
    $142pernight
    All the Cruise Line Offers & More:
    • Limited-Time Exclusive: Earn 2 Points per eligible $1 spent
    • Member Exclusive: Earn up to 10,000 bonus points on eligible sailings!
    • Rapid Rewards® Member Base Offer: Earn 1 point per eligible $1 spent
    • Drop & Go Sale: Limited Time Reduced Rates!
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Here Comes the Sun Sale: Save up to 40%
     
    Interior from $1,749
    ($97pernight)
    4.4 rating out of 5  (418 reviews)
  • Majestic Princess
    4.4 rating out of 5  (418 reviews)

    18 Night Andes & South America

    Majestic Princess

    Departing from: San Pedro (Los Angeles), California
    Ports of Call:
    • Puerto Vallarta, Mexico
    • Panama City (Fuerte Amador), Panama
    • Callao (Lima), Peru
    • Pisco (Nazca Lines), Peru
    • Coquimbo (La Serena), Chile
    • San Antonio (Santiago), Chile
    Sailing Dates:
    • December 2024
    interior from
    $1,079
    $60pernight
    oceanview from
    Not Available
    balcony from
    $1,399
    $78pernight
    suite from
    $1,709
    $95pernight
    All the Cruise Line Offers & More:
    • Limited-Time Exclusive: Earn 2 Points per eligible $1 spent
    • Member Exclusive: Earn up to 10,000 bonus points on eligible sailings!
    • Rapid Rewards® Member Base Offer: Earn 1 point per eligible $1 spent
    • Drop & Go Sale: Limited Time Reduced Rates!
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Here Comes the Sun Sale: Save up to 40%
     
    Interior from $1,079
    ($60pernight)
    4.4 rating out of 5  (418 reviews)
  • Norwegian Star
    3.6 rating out of 5  (2,048 reviews)

    16 Night Transatlantic: Brazil & Canary Islands

    Norwegian Star

    Departing from: Rio De Janeiro, Brazil
    Ports of Call:
    • Buzios, Brazil
    • Salvador De Bahia, Brazil
    • Maceio, Brazil
    • Recife, Brazil
    • Porto Grande, Cape Verde Islands
    • Santa Cruz De Tenerife, Canary Islands
    • Las Palmas, Gran Canaria, Canary Islands
    • Funchal, Madeira, Portugal
    • Lisbon, Portugal
    Sailing Dates:
    • March 2025
    interior from
    $1,472
    $92pernight
    oceanview from
    $1,723
    $108pernight
    balcony from
    $2,652
    $166pernight
    suite from
    $2,852
    $178pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Limited-Time Exclusive: Earn 2 Points per eligible $1 spent
    • Member Exclusive: Earn up to 10,000 bonus points on eligible sailings!
    • Exclusive: Gratuities Included for 2
    • Rapid Rewards® Member Base Offer: Earn 1 point per eligible $1 spent
    • 70% off 2nd Guest + Enhanced More at Sea Perks
     
    Interior from $1,472
    ($92pernight)
    3.6 rating out of 5  (2,048 reviews)
  • Sapphire Princess
    4 rating out of 5  (568 reviews)

    14 Night Cape Horn & Strait of Magellan

    Sapphire Princess

    Departing from: San Antonio (Santiago), Chile
    Ports of Call:
    • Puerto Montt, Chile
    • Cruise Amalia Glacier
    • Punta Arenas, Chile
    • Ushuaia, Tierra Del Fuego, Argentina
    • Cruise Cape Horn
    • Port Stanley, Falkland Islands
    • Puerto Madryn, Argentina
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    Sailing Dates:
    • February 2025
    interior from
    $3,075
    $220pernight
    oceanview from
    $3,114
    $222pernight
    balcony from
    $4,669
    $334pernight
    suite from
    $4,709
    $336pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Limited-Time Exclusive: Earn 2 Points per eligible $1 spent
    • Member Exclusive: Earn up to 10,000 bonus points on eligible sailings!
    • Rapid Rewards® Member Base Offer: Earn 1 point per eligible $1 spent
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Here Comes the Sun Sale: Save up to 40%
     
    Interior from $3,075
    ($220pernight)
    4 rating out of 5  (568 reviews)
  • Oosterdam
    4.1 rating out of 5  (887 reviews)

    14 Night South America Passage

    Oosterdam

    Departing from: San Antonio (Santiago), Chile
    Ports of Call:
    • Puerto Montt, Chile
    • Puerto Chacabuco, Chile
    • Cruise Chilean Fjords
    • Scenic Cruising Sarmiento Channel
    • Cruise Strait Of Magellan
    • Punta Arenas, Chile
    • Cruise Cockburn & Beagle Channels
    • Cruise Glacier Alley
    • Ushuaia, Tierra Del Fuego, Argentina
    • Cruise Cape Horn
    • Port Stanley, Falkland Islands
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    Sailing Dates:
    • December 2025
    • February 2026
    interior from
    $2,059
    $147pernight
    oceanview from
    $2,259
    $161pernight
    balcony from
    $3,174
    $227pernight
    suite from
    $4,194
    $300pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Limited-Time Exclusive: Earn 2 Points per eligible $1 spent
    • Member Exclusive: Earn up to 10,000 bonus points on eligible sailings!
    • Rapid Rewards® Member Base Offer: Earn 1 point per eligible $1 spent
    • Free Elite Beverage Package, Gratuities Included & More on Select Fares
     
    Interior from $2,059
    ($147pernight)
    4.1 rating out of 5  (887 reviews)
  • Celebrity Equinox
    4.3 rating out of 5  (1,915 reviews)

    14 Night Patagonia & Argentina

    Celebrity Equinox

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Port Stanley, Falkland Islands
    • Cruise Cape Horn
    • Ushuaia, Tierra Del Fuego, Argentina
    • Cruise Strait Of Magellan
    • Punta Arenas, Chile
    • Puerto Madryn, Argentina
    • Punta Del Este, Uruguay
    Sailing Dates:
    • December 2025
    • February 2026
    interior from
    $2,290
    $164pernight
    oceanview from
    $2,540
    $181pernight
    balcony from
    $2,869
    $205pernight
    suite from
    $6,518
    $466pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Limited-Time Exclusive: Earn 2 Points per eligible $1 spent
    • Member Exclusive: Earn up to 10,000 bonus points on eligible sailings!
    • CALL: up to a $75 FREE Dining Credit!
    • Rapid Rewards® Member Base Offer: Earn 1 point per eligible $1 spent
    • All-Included: Free Drinks & Wi-Fi
     
    Interior from $2,290
    ($164pernight)
    4.3 rating out of 5  (1,915 reviews)
  • Sapphire Princess
    4 rating out of 5  (568 reviews)

    14 Night Cape Horn & Strait of Magellan

    Sapphire Princess

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Puerto Madryn, Argentina
    • Port Stanley, Falkland Islands
    • Cruise Cape Horn
    • Ushuaia, Tierra Del Fuego, Argentina
    • Punta Arenas, Chile
    • Cruise Amalia Glacier
    • Puerto Montt, Chile
    • San Antonio (Santiago), Chile
    Sailing Dates:
    • February 2025
    • March 2025
    interior from
    $2,538
    $181pernight
    oceanview from
    $2,633
    $188pernight
    balcony from
    $4,558
    $326pernight
    suite from
    $6,238
    $446pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Limited-Time Exclusive: Earn 2 Points per eligible $1 spent
    • Member Exclusive: Earn up to 10,000 bonus points on eligible sailings!
    • Rapid Rewards® Member Base Offer: Earn 1 point per eligible $1 spent
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Here Comes the Sun Sale: Save up to 40%
     
    Interior from $2,538
    ($181pernight)
    4 rating out of 5  (568 reviews)
  • Oosterdam
    4.1 rating out of 5  (887 reviews)

    14 Night South America Passage

    Oosterdam

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Port Stanley, Falkland Islands
    • Cruise Cape Horn
    • Ushuaia, Tierra Del Fuego, Argentina
    • Cruise Beagle Channel
    • Cruise Glacier Alley
    • Cruise Strait Of Magellan
    • Punta Arenas, Chile
    • Cruise Cockburn Channel
    • Cruise Strait Of Magellan
    • Puerto Montt, Chile
    • San Antonio (Santiago), Chile
    Sailing Dates:
    • March 2026
    interior from
    $2,209
    $158pernight
    oceanview from
    $2,409
    $172pernight
    balcony from
    $3,454
    $247pernight
    suite from
    $4,509
    $322pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Member Exclusive: Earn up to 10,000 bonus points on eligible sailings!
    • Rapid Rewards® Member Base Offer: Earn 1 point per eligible $1 spent
    • Free Elite Beverage Package, Gratuities Included & More on Select Fares
     
    Interior from $2,209
    ($158pernight)
    4.1 rating out of 5  (887 reviews)
  • Norwegian Jade
    3.9 rating out of 5  (1,402 reviews)

    17 Night South America: Cabo & Trujillo

    Norwegian Jade

    Departing from: Callao (Lima), Peru
    Ports of Call:
    • Salaverry (Trujillo), Peru
    • Manta, Ecuador
    • Panama City, Panama
    • Puntarenas, Costa Rica
    • San Juan Del Sur, Nicaragua
    • Acajutla, El Salvador
    • Puerto Quetzal, Guatemala
    • Huatulco, Mexico
    • Acapulco, Mexico
    • Manzanillo, Mexico
    • Puerto Vallarta, Mexico
    • Cabo San Lucas, Mexico
    • San Diego, California
    Sailing Dates:
    • March 2026
    interior from
    $2,081
    $122pernight
    oceanview from
    $2,591
    $152pernight
    balcony from
    $4,041
    $238pernight
    suite from
    $4,829
    $284pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Member Exclusive: Earn up to 10,000 bonus points on eligible sailings!
    • Exclusive: Gratuities Included for 2
    • Rapid Rewards® Member Base Offer: Earn 1 point per eligible $1 spent
    • 70% off 2nd Guest + Enhanced More at Sea Perks
     
    Interior from $2,081
    ($122pernight)
    3.9 rating out of 5  (1,402 reviews)
  • Celebrity Equinox
    4.3 rating out of 5  (1,915 reviews)

    14 Night Patagonia & Argentina Holiday

    Celebrity Equinox

    Departing from: Buenos Aires, Argentina
    Ports of Call:
    • Montevideo, Uruguay
    • Port Stanley, Falkland Islands
    • Cruise Cape Horn
    • Ushuaia, Tierra Del Fuego, Argentina
    • Cruise Strait Of Magellan
    • Punta Arenas, Chile
    • Puerto Madryn, Argentina
    • Punta Del Este, Uruguay
    Sailing Dates:
    • December 2025
    interior from
    $2,467
    $176pernight
    oceanview from
    $2,649
    $189pernight
    balcony from
    $3,530
    $252pernight
    suite from
    $7,900
    $564pernight
    All the Cruise Line Offers & More:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Limited-Time Exclusive: Earn 2 Points per eligible $1 spent
    • Member Exclusive: Earn up to 10,000 bonus points on eligible sailings!
    • CALL: up to a $75 FREE Dining Credit!
    • Rapid Rewards® Member Base Offer: Earn 1 point per eligible $1 spent
    • All-Included: Free Drinks & Wi-Fi
     
    Interior from $2,467
    ($176pernight)
    4.3 rating out of 5  (1,915 reviews)
  • Majestic Princess
    4.4 rating out of 5  (418 reviews)

    15 Night Cape Horn & Strait of Magellan

    Majestic Princess

    Departing from: San Antonio (Santiago), Chile
    Ports of Call:
    • Puerto Montt, Chile
    • Cruise Amalia Glacier
    • Punta Arenas, Chile
    • Ushuaia, Tierra Del Fuego, Argentina
    • Cruise Cape Horn
    • Port Stanley, Falkland Islands
    • Puerto Madryn, Argentina
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    Sailing Dates:
    • December 2024
    interior from
    Call for availability
    oceanview from
    Not Available
    balcony from
    $3,429
    $229pernight
    suite from
    $3,949
    $263pernight
    All the Cruise Line Offers & More:
    • Limited-Time Exclusive: Earn 2 Points per eligible $1 spent
    • Member Exclusive: Earn up to 10,000 bonus points on eligible sailings!
    • Rapid Rewards® Member Base Offer: Earn 1 point per eligible $1 spent
    • Drop & Go Sale: Limited Time Reduced Rates!
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Here Comes the Sun Sale: Save up to 40%
     
    Balcony from $3,429
    ($229pernight)
    4.4 rating out of 5  (418 reviews)
  • Azamara Journey
    4.3 rating out of 5  (139 reviews)

    10 Night Peru & Chile Voyage

    Azamara Journey

    Departing from: Callao (Lima), Peru
    Ports of Call:
    • Pisco (Nazca Lines), Peru
    • Arica, Chile
    • Iquique, Chile
    • Antofagasta, Chile
    • Coquimbo (La Serena), Chile
    • San Antonio (Santiago), Chile
    Sailing Dates:
    • January 2025
    interior from
    $1,629
    $163pernight
    oceanview from
    $1,679
    $168pernight
    balcony from
    Call for availability
    suite from
    $5,929
    $593pernight
    All the Cruise Line Offers & More:
    • Up to $500 to Spend on Board
    • Choose: Complimentary Beverage Package or Unlimited Wi-Fi
    • Limited-Time Exclusive: Earn 2 Points per eligible $1 spent
    • Rapid Rewards® Member Base Offer: Earn 1 point per eligible $1 spent
     
    Interior from $1,629
    ($163pernight)
    4.3 rating out of 5  (139 reviews)
  • Viking Sea
    4.4 rating out of 5  (83 reviews)

    12 Night Amazon & Caribbean Adventure

    Viking Sea

    Departing from: Manaus (Amazon River), Brazil
    Ports of Call:
    • Parintins (Amazon River), Brazil
    • Santarem (Amazon River), Brazil
    • Cruise Amazon River
    • Devils Island, French Guiana
    • Bridgetown, Barbados
    • Castries, St. Lucia
    • Basseterre, St. Kitts
    • San Juan, Puerto Rico
    Sailing Dates:
    • December 2024
    • March 2025
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $4,799
    $400pernight
    suite from
    $7,999
    $667pernight
    All the Cruise Line Offers & More:
    • Limited-Time Exclusive: Earn 2 Points per eligible $1 spent
    • Rapid Rewards® Member Base Offer: Earn 1 point per eligible $1 spent
     
    Balcony from $4,799
    ($400pernight)
    4.4 rating out of 5  (83 reviews)
  • Viking Sea
    4.4 rating out of 5  (83 reviews)

    12 Night Amazon & Caribbean Adventure

    Viking Sea

    Departing from: San Juan, Puerto Rico
    Ports of Call:
    • St. Johns, Antigua
    • Castries, St. Lucia
    • Bridgetown, Barbados
    • Devils Island, French Guiana
    • Cruise Amazon River
    • Santarem (Amazon River), Brazil
    • Parintins (Amazon River), Brazil
    • Manaus (Amazon River), Brazil
    Sailing Dates:
    • November 2024
    • February 2025
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $4,999
    $417pernight
    suite from
    $6,999
    $583pernight
    All the Cruise Line Offers & More:
    • Limited-Time Exclusive: Earn 2 Points per eligible $1 spent
    • Rapid Rewards® Member Base Offer: Earn 1 point per eligible $1 spent
     
    Balcony from $4,999
    ($417pernight)
    4.4 rating out of 5  (83 reviews)

Experience the Thrill of a South America Cruise

Get the Best Deals on a South America Cruise

Take pleasure in a cruise adventure of a lifetime when you travel to South America with Southwest Cruises.

Your sailing will begin from the always chic and star-studded city of Miami, FL. Enjoy South Florida’s most famed district by soaking up the sun on South Beach, dine in a beachside restaurant or relax at an outdoor café.

Aboard a grand ship, you’ll set sail for places like Cartagena, a city known for its exterior beauty resting on the northern coast of Columbia in the Caribbean Coast Region. Colon, Panama is a popular cruise destination, and one you won’t want to miss. Its main attraction, arguably, is the infamous Panama Canal, one of the world’s greatest engineering feats made by man.

To the east, your South America cruise itineraries include ports like Santos (Sao Paulo), Brazil, where the soft sands of the beaches connect with the crystal blue waters of the Atlantic. In Buenos Aires, visit Plaza Intendente Alvear, an event livened area littered with street performers, colorful crafts and souvenir markets. Lose yourself in the street fairs of Montevideo, Uruguay and indulge in a local dish, or shop till you drop in one of many specialty boutiques.

A South America cruise with Southwest Cruises offers a wide-range of diverse pleasure-seeking activities such as shopping, exceptional sightseeing, beach fun, new dining experiences and more.

South America Cruises